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Neurophysin I (K40) polyclonal antibody

货号: BS3475

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS3475

Product Name :Neurophysin I (K40) polyclonal antibody

Swiss-Prot :P01178

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :Neurophysin I (NPI) and neurophysin II (NPII) function as carrier proteins for oxytocin and vasopressin, respectively. Oxytocin is a pituitary hormone which induces uterine contractions during childbirth and the ejection of milk from the mammary glands during nursing. Vasopressin is involved in the metabolism of water and electrolytes and has been identified as a vasoconstrictor. Both neurophysin genes exist as three exons, with each exon encoding a functional protein domain. Studies show that the identically conserved middle region (exon B) is involved in NP-NP homodimer formation as well as being the site for the glycine 17 to valine point mutation responsible for familial diabetes insipidus.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Neurophysin I (K40) polyclonal antibody detects endogenous levels of Neurophysin I protein.

BiowMW :~ 13 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Oxytocin-neurophysin 1; OT-NPI; Oxytocin; Ocytocin; Neurophysin 1; OXT; OT

Immunogen :Synthetic peptide, corresponding to amino acids 11-60 of Human Neurophysin I.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Neurophysin I (K40) pAb at 1:500 dilution Lane1:A549 whole cell lysate(20ug) Lane2:SGC7901 whole cell lysate(40ug) Lane3:3T3-L1 whole cell lysate(40ug) Lane4:H9C2 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of Neurophysin I (K40) pAb in paraffin-embedded human brain tissue.