Product Name :Cathepsin E (I292) polyclonal antibody
Reactivity :Human,Mouse,Rat
Application_all :IHC: 1:50~1:200
Background :Cathepsin E is an intracellular aspartic protease of the pepsin family, which is structurally highly homologous to the lysosomal aspartic protease cathepsin D. Cathepsin E is less abundant than Cathepsin D and has a more limited distribution, which includes lymphoid tissues, gastrointestinal tract tissue, blood cells, microglia and activated B lymphocytes. It is not expressed in resting B lymphocytes.Cathepsin E may have a role in immune function. It is most likely involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. It may also play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Cathepsin E (I292) polyclonal antibody detects endogenous levels of Cathepsin E protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Cathepsin E; CTSE
Immunogen :Synthetic peptide, corresponding to amino acids 260-310 of Human Cathepsin E.
Modification :Unmodification
