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T-type Ca++ CP α1H (P492) polyclonal antibody（KU）

货号: BS3413

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS3413

Product Name :T-type Ca++ CP α1H (P492) polyclonal antibody（KU）

Swiss-Prot :O95180

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Voltage-dependent Ca++ channels mediate Ca++ entry into excitable cells in response to membrane depolarization, and they are involved in a variety of Ca++-dependent processes, including muscle contraction, hormone or neurotransmitter release and gene expression. Calcium channels are highly diverse, multimeric complexes composed of an α1 subunit, an intracellular β subunit, a disulfide linked α2/δ subunit and a transmembrane γ subunit. Ca++ currents are characterized on the basis of their biophysical and pharmacologic properties and include L-, N-, T-, P-, Q-, and R- types. T-type Ca++ currents are activated and inactivated more rapidly and at more negative membrane potentials than other Ca++ current types. T-type Ca++ channels enhance odor sensitivity by lowering the threshold of spike generation in olfactory receptor cells (ORCs).

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :T-type Ca++ CP α1H (P492) polyclonal antibody detects endogenous levels of T-type Ca++ CP α1H protein.

BiowMW :~ 315 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Voltage-dependent T-type calcium channel subunit alpha-1H; Low-voltage-activated calcium channel alpha1 3.2 subunit; Voltage-gated calcium channel subunit alpha Cav3.2; CACNA1H

Immunogen :Synthetic peptide, corresponding to amino acids 461-510 of Human T-type Ca++ CP α1H.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of T-type Ca++ CP α1H (P492) pAb at 1:500 dilution Lane1:L02 whole cell lysate(40ug) Lane2:HepG2 whole cell lysate(40ug) Lane3:PC3 whole cell lysate(20ug) Lane4:AML-12 whole cell lysate(40ug) Lane5:H9C2 whole cell lysate(40ug)