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Cdc40 (S209) polyclonal antibody（KU）

货号: BS3374

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS3374

Product Name :Cdc40 (S209) polyclonal antibody（KU）

Swiss-Prot :O60508

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :Cdc40, also known as pre-mRNA-processing factor 17 (PRPF17) or EH-binding protein 3 (EHB3), is a 579 amino acid nuclear protein. Cdc40 is essential for the catalytic step II of the pre-mRNA splicing process, in which Cdc40 associates with the spliceosome C complex. Cdc40 contains seven WD repeats, which are important in protein-protein interactions. Cdc40 has sequence similarity to the yeast protein Prp17, which is involved in pre-mRNA splicing and cell cycle progression. The sequence similarity between the mammalian Cdc40 and the yeast Prp17 may indicate an additional role in cell cycle progression for mammalian Cdc40.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Cdc40 (S209) polyclonal antibody detects endogenous levels of Cdc40 protein.

BiowMW :~ 65 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Pre-mRNA-processing factor 17; Cell division cycle 40 homolog; EH-binding protein 3; Ehb3; PRP17 homolog; hPRP17; CDC40; EHB3; PRP17; PRPF17

Immunogen :Synthetic peptide, corresponding to amino acids 181-230 of Human Cdc40.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Cdc40 (S209) pAb at 1:500 dilution Lane1:HEK293T whole cell lysate(10ug) Lane2:MCF-7 whole cell lysate(10ug) Lane3:CT26 whole cell lysate(10ug) Lane4:The Brain tissue lysate of Rat(40ug)

Immunohistochemistry (IHC) analyzes of Cdc40 (S209) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.