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SLC22A3 (Q306) polyclonal antibody（KU）

货号: BS3359

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS3359

Product Name :SLC22A3 (Q306) polyclonal antibody（KU）

Swiss-Prot :O75751

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Organic cation transporters (OCT) are expressed in the plasma membrane of epithelial cells from a wide range of tissues, where they function in the elimination of endogenous amines, cationic drugs and other xenobiotics. The structure of OCTs consists of a 12-transmembrane-domain structure and a large extracellular hydrophilic loop. In humans, OCT1 is primarily expressed in the liver while OCT2 is expressed in the kidney. OCT3 is expressed in the placenta, skeletal muscle, prostate, aorta and liver. OCT3, also known as extraneuronal monoamine transporter, is widely expressed in different regions of the brain including the hippocampus, cerebellum and cerebral cortex. OCT3 mediates the uptake of several neuroactive agents, including dopamine, and may play an important role in the disposition of neurotransmitters and cationic neurotoxins in the brain.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :SLC22A3 (Q306) polyclonal antibody detects endogenous levels of SLC22A3 protein.

BiowMW :~ 61 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Solute carrier family 22 member 3; Extraneuronal monoamine transporter; EMT; Organic cation transporter 3; SLC22A3; EMTH; OCT3

Immunogen :Synthetic peptide, corresponding to amino acids 281-330 of Human SLC22A3.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of SLC22A3 (Q306) polyclonal antibody at 1:500 dilution Lane1:786-O whole cell lysate(40ug) Lane2:L02 whole cell lysate(40ug) Lane3:HEK293T whole cell lysate(40ug)