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COP ζ1 (I48) polyclonal antibody（KU）

货号: BS3287

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS3287

Product Name :COP ζ1 (I48) polyclonal antibody（KU）

Swiss-Prot :P61923

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :Membrane and vesicular trafficking in the early secretory pathway are mediated by non-Clathrin COP (coat protein) I-coated vesicles. COPI-coated vesicles mediate retrograde transport from the Golgi back to the ER and intra-Golgi transport. The cytosolic precursor of the COPI coat, the heptameric coatomer complex, is composed of two subcomplexes. The first consists of the COPB, COPG, COPD and COPZ1 subunits (also known as β-COP, γ-COP, δ-COP and ζ-1 COP, respectively), which are distantly homologous to AP Clathrin adaptor subunits. The second consists of the COPA, COPP and COPE subunits (also known as α-COP, COPP and ε-COP, respectively).

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :COP ζ1 (I48) polyclonal antibody detects endogenous levels of COP ζ1 protein.

BiowMW :~ 20 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Coatomer subunit zeta-1; Zeta-1-coat protein; Zeta-1 COP; COPZ1; COPZ; CGI-120; HSPC181; COP ζ-1

Immunogen :Synthetic peptide, corresponding to the N-terminus of Human COP ζ1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of COP ζ1 (I48) polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate Lane2:HEK293T cell lysate Lane3:sp2/0 cell lysate Lane4:H9C2 cell lysate Lane5:PC12 cell lysate

Immunohistochemistry (IHC) analyzes of COP ζ1 (I48) pAb in paraffin-embedded human esophageal carcinoma tissue at 1:50.showing Nucleus speckle and Cytoplasm staining. Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.

Immunohistochemistry (IHC) analyzes of COP ζ1 (I48) pAb in paraffin-embedded human stomach carcinoma tissue at 1:50.showing Nucleus speckle and Cytoplasm staining. Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.