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mAChR M4 (P277) polyclonal antibody（KU）

货号: BS3236

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS3236

Product Name :mAChR M4 (P277) polyclonal antibody（KU）

Swiss-Prot :P08173

Host :Rabbit

Reactivity :Human,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The muscarinic acetylcholine receptors (mAChR) mediate a variety of cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels. The mAChRs transducer signals by coupling to G-proteins, which then modulate several downstream effector proteins and ion channels. Five mAChR subtypes have been identified, designated M1 to M5. The five receptor subtypes show distinct patterns of tissue distribution, as well as distinct pharmacological and functional properties.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :mAChR M4 (P277) polyclonal antibody detects endogenous levels of mAChR M4 protein

BiowMW :~ 53 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Muscarinic acetylcholine receptor M4,CHRM4

Immunogen :Synthetic peptide, corresponding to amino acids 241-290 of Human mAChR M4.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of mAChR M4 (P277) pAb at 1:500 dilution Lane1:H1792 whole cell lysate(40ug) Lane2:MCF-7 whole cell lysate(40ug) Lane3:K562 whole cell lysate(40ug) Lane4:C6 whole cell lysate(40ug) Lane5:SP2/0 whole cell lysate(40ug)