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MRP7 (E865) polyclonal antibody（KU）

货号: BS3144

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS3144

Product Name :MRP7 (E865) polyclonal antibody（KU）

Swiss-Prot :Q5T3U5

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The MRP family is represented by nine similar ABC transporters that have the ability to transport structurally diverse lipophilic anions and operate as chemical efflux pumps. MRP7 (multidrug resistance-associated protein 7, ATPbinding cassette sub-family C member 10) is a multi-pass membrane protein that belongs to the ABC transporter family (conjugate transporter subfamily). MRP7 is involved with the ATP-dependent transport of 17β-estradiol-D-17-β-glucuronide (E217βG). MRP7 is also probably involved in cellular detoxification through its lipophilic anion extrusion capabilities. MRP7 contains two ABC transmembrane type 1 domains and two ABC transporter domains. MRP7 likely has three isoforms. Isoform 2 is the most widely expressed, while isoform 1 is predominately expressed in the spleen.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :MRP7 (E865) polyclonal antibody detects endogenous levels of MRP7 protein.

BiowMW :~ 162 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Multidrug resistance-associated protein 7; ATP-binding cassette sub-family C member 10; ABCC10; MRP7; SIMRP7

Immunogen :Synthetic peptide, corresponding to amino acids 834-887 of Human MRP7.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of MRP7 (E865) polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:PC12 whole cell lysate