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SLC16A13 (L423) polyclonal antibody（KU）

货号: BS3143

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS3143

Product Name :SLC16A13 (L423) polyclonal antibody（KU）

Swiss-Prot :Q7RTY0

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Monocarboxylates, such as lactate and pyruvate, play an integral role in cellular metabolism. Lactic acid is produced in large quantities as a result of glycolysis, which provides the majority of ATP to cells under normal physiological conditions. However, accumulation of lactic acid leads to a decrease in intracellular pH and, thus, to a cessation of glycolysis. In order for glycolysis to continue at a high rate, lactic acid must be transported out of the cell. This transport process is carried out by a family of monocarboxylate transporters (MCTs), which function as proton symports and are stereoselective for L-lactate. MCT13 (Monocarboxylate transporter 13), also known as SLC16A13 (Solute carrier family 16 member 13), is a 426 amino acid multi-pass membrane protein that belongs to the MCT transport family. Functioning as a proton-linked monocarboxylate transporter, MCT13 catalyzes the rapid transports of molecules, such as lactate, across the plasma membrane.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :SLC16A13 (L423) polyclonal antibody detects endogenous levels of SLC16A13 protein.

BiowMW :~ 40 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Monocarboxylate transporter 13; MCT 13; Solute carrier family 16 member 13; SLC16A13; MCT13

Immunogen :Synthetic peptide, corresponding to amino acids 389-442 of Human SLC16A13.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of SLC16A13 (L423) pAb at 1:500 dilution Lane1:C6 whole cell lysate(40ug) Lane2:3T3-L1 whole cell lysate(40ug) Lane3:MCF-7 whole cell lysate(40ug) Lane4:HepG2 whole cell lysate(40ug) Lane5:H1792 whole cell lysate(20ug)