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MED18 (V102) polyclonal antibody（KU）

货号: BS3141

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS3141

Product Name :MED18 (V102) polyclonal antibody（KU）

Swiss-Prot :Q9BUE0

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :In mammalian cells, transcription is regulated in part by high molecular weight co-activating complexes that mediate signals between transcriptional activators and RNA polymerase II (Pol II). The mediator complex is one such multi-protein structure that functions as a bridge between regulatory proteins and Pol II, thereby regulating Pol II-dependent transcription. Med18 (mediator complex subunit 18), also known asp28b, is a 208 amino acid protein that localizes to nucleus and exists as a component of the mediator complex. Working in tandem with several other proteins, including Med8 and Med25, Med18 serves as a scaffold for the assembly of a functional preinitiation complex with Pol II and general transcription factors, thereby activating the transcription of Pol II-dependent genes.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :MED18 (V102) polyclonal antibody detects endogenous levels of MED18 protein.

BiowMW :~ 24 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Mediator of RNA polymerase II transcription subunit 18; Mediator complex subunit 18; p28b; MED18

Immunogen :Synthetic peptide, corresponding to amino acids 72-120 of Human MED18.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of MED18 (V102) pAb at 1:1000 dilution Lane1:HepG2 whole cell lysate(20ug) Lane2:SGC7901 whole cell lysate(20ug) Lane3:The Brain tissue lysate of Rat(40ug) Lane4:The Brain tissue lysate of Mouse(40ug)