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LYPLA1 (K90) polyclonal antibody（KU）

货号: BS3063

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS3063

Product Name :LYPLA1 (K90) polyclonal antibody（KU）

Swiss-Prot :O75608

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :Acyl-protein thioesterase 1 (APT1, Lysophospholipase 1) is a member of a family of critical enzymes, lysophospholipases, that act on biological membranes to regulate the multifunctional lysophospholipids. APT1 hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. The role of APT1 in regulating lysophospholipids is important because increased levels of lysophospholipids are detected in a variety of diseases, including atherosclerosis and hyperlipidemia. Regulated expression of acyl-protein thioesterase by PKC has been suggested to have important implications for signal transduction processes.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :LYPLA1 (K90) polyclonal antibody detects endogenous levels of LYPLA1 protein.

BiowMW :~ 25 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Acyl-protein thioesterase 1; APT-1; hAPT1; Lysophospholipase 1; Lysophospholipase I; LPL-I; LysoPLA I; LYPLA1; APT1; LPL1

Immunogen :Synthetic peptide, corresponding to amino acids 61-110 of Human LYPLA1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of LYPLA1 (K90) polyclonal antibody at 1:500 dilution Lane1:A549 whole cell lysate Lane2:Mouse liver tissue lysate Lane3:Rat liver tissue lysate

Immunohistochemistry (IHC) analyzes of LYPLA1 (K90) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.

Palmitoyltransferase DHHC9 and acyl protein thioesterase APT1 modulate renal fibrosis through regulating β-catenin palmitoylation

JournalNature Communications

ApplicationWB

IF16.6

SpeciesMouse

PMID37865665