Product Name :VAMP-1/2/3 (D70) polyclonal antibody
Swiss-Prot :P23763/P63027/Q15836
Reactivity :Human,Mouse,Rat
Application_all :IHC:1:50~1:200
Background :VAMPs, also designated synaptobrevins, including VAMP-1 and VAMP-2, and synaptotagmin, a protein that may function as an inhibitor of exocytosis, are vesicular proteins. SNAPs, including a- and g-SNAP, are cytoplasmic proteins that bind to a membrane receptor complex composed of VAMP, SNAP 25 and Syntaxin. SNAPs mediate the membrane binding of NSF, which is essential for membrane fusion reactions. An additional protein designated synaptophysin may regulate exo-cytosis by competing with SNAP 25 and syntaxins for VAMP binding.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :VAMP-1/2/3 (D70) polyclonal antibody detects endogenous levels of VAMP-1/VAMP-2/VAMP-3 protein
Note :For research use only, not for use in diagnostic procedure.
Pathway :Vesicle Trafficking presynaptic signaling,AMPK Signaling Pathway,
Alternative Name :Vesicle-associated membrane protein 1; VAMP-1; Synaptobrevin-1; VAMP1; SYB1; Vesicle-associated membrane protein 2; VAMP-2; Synaptobrevin-2; VAMP2; SYB2; Vesicle-associated membrane protein 3; VAMP-3; Cellubrevin; CEB; Synaptobrevin-3; VAMP3; SYB3
Immunogen :Synthetic peptide, corresponding to amino acids 40-90 of Human VAMP1.
Modification :Unmodification
