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mAChR M2 (P224) polyclonal antibody（KU）

货号: BS2781

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS2781

Product Name :mAChR M2 (P224) polyclonal antibody（KU）

Swiss-Prot :P08172

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Background :The muscarinic acetylcholine receptors (mAChR) mediate a variety of cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels. The mAChRs transducer signals by coupling to G-proteins, which then modulate several downstream effector proteins and ion channels. Five mAChR subtypes have been identified, designated M1 to M5. The five receptor subtypes show distinct patterns of tissue distribution, as well as distinct pharmacological and functional properties.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :mAChR M2 (P224) polyclonal antibody detects endogenous levels of mAChR M2 protein.

BiowMW :~ 52 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CHRM2; Muscarinic acetylcholine receptor M2

Immunogen :Synthetic peptide, corresponding to amino acids 191-240 of Human mAChR M2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of mAChR M2 (P224) pAb at 1:1000 dilution Lane1:CT26 whole cell lysate(40ug) Lane2:PC12 whole cell lysate(40ug) Lane3:Hela whole cell lysate(40ug) Lane4:SGC7901 whole cell lysate(40ug) Lane5:HEK293T whole cell lysate(40ug)