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mAChR M1 (R336) polyclonal antibody

货号: BS2708

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS2708

Product Name :mAChR M1 (R336) polyclonal antibody

Swiss-Prot :P11229

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :The muscarinic acetylcholine receptors (mAChR) mediate a variety of cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels. The mAChRs transducer signals by coupling to G-proteins, which then modulate several downstream effector proteins and ion channels. Five mAChR subtypes have been identified, designated M1 to M5. The five receptor subtypes show distinct patterns of tissue distribution, as well as distinct pharmacological and functional properties. The amino acid sequence of each mAChR subtype reflects a structure that is characteristic of G-protein coupled receptors, consisting of seven highly conserved transmembrane segments and a large intracellular region unique to each subtype, which constitutes the effector-coupling domain.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :mAChR M1 (R336) polyclonal antibody detects endogenous levels of mAChR M1 protein.

BiowMW :~ 50 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CHRM1 ; ACM1 ; Muscarinic acetylcholine receptor M1

Immunogen :Synthetic peptide, corresponding to amino acids 311-360 of Human mAChR M1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of mAChR M1 (R336) polyclonal antibody in extracts from hela cells.

Adiponectin-Receptor Agonistic Dipeptide Tyr–Pro Stimulates the Acetylcholine Nervous System in NE-4C Cells

JournalJOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

ApplicationWB

IF6.1

SpeciesMouse

PMID38511275