产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

Spindlin-1 (H139) polyclonal antibody（KU）

货号: BS2678

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS2678

Product Name :Spindlin-1 (H139) polyclonal antibody（KU）

Swiss-Prot :Q9Y657

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :SPIN1 (spindlin 1), also known as SPIN or ovarian cancer-related protein (OCR), is a 262 amino acid nuclear protein suggested to play a role in regulation of the cell-cycle during the transition from gamete to embryo. A member of the SPIN/STSY family, SPIN1 localizes to interphase nucleus and mitotic chromosomes, and is modified by phosphorylation in a cell-cycle-dependent fashion. A meiotic spindle-binding protein, SPIN1 overexpression has been shown to cause defects in mitotic spindles, thereby resulting in chromosome instability and potential tumorigenesis.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Spindlin-1 (H139) polyclonal antibody detects endogenous levels of Spindlin-1 protein.

BiowMW :~ 30 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :OCR; Ovarian cancer-related protein; SPIN; Spin1; SPIN1; Spindlin 1;

Immunogen :Synthetic peptide, corresponding to amino acids 110-156 of Human Spindlin-1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Spindlin-1 (H139) pAb at 1:500 dilution Lane1:SK-OVCAR3 whole cell lysate(40ug) Lane2:SGC7901 whole cell lysate(40ug) Lane3:The Ovarian tissue lysate of Rat(40ug) Lane4:The Testis tissue lysate of Mouse(40ug)

Immunohistochemistry (IHC) analyzes of Spindlin-1 (H139) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.