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Matriptase (K21) polyclonal antibody（KU）

货号: BS2574

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS2574

Product Name :Matriptase (K21) polyclonal antibody（KU）

Swiss-Prot :Q9Y5Y6

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF IP

Application_all :WB: 1:500~1:1000 IHC/IF: 1:50~1:200 IP: 1:10~1:100

Background :Matriptase (also known as MT-SP1, ST14, prostamin and epithin in mouse) is a tumor-associated type II transmembrane serine protease that is highly expressed in many human cancer-derived cell lines and is implicated in extracellular matrix re-modeling, tumor growth, and metastasis. Matriptase performs pleiotropic functions in the development of the epidermis, hair follicles, and cellular immune system. Sphingosine 1-phosphate (S1P, SPP), present in serum-derived lipoproteins, activates matriptase while matriptase activates both urokinase-type plasminogen activator and hepatocyte growth factor (HGF). Hepatocyte growth factor activator inhibitor type 1 (HAI-1) is a Kunitz-type serine protease inhibitor identified as a strong inhibitor of matriptase and HGF.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Matriptase (K21) polyclonal antibody detects endogenous levels of Matriptase protein.

BiowMW :~ 90 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Suppressor of tumorigenicity 14 protein; Matriptase; Membrane-type serine protease 1; MT-SP1; Prostamin; Serine protease 14; Serine protease TADG-15; Tumor-associated differentially-expressed gene 15 protein; ST14; PRSS14; SNC19; TADG15

Immunogen :Synthetic peptide, corresponding to the N-terminual of Human Matriptase.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Matriptase (K21) pAb at 1:500 dilution Lane1:C6 whole cell lysate(40ug) Lane2:CT26 whole cell lysate(40ug) Lane3:HCT116 whole cell lysate(40ug) Lane4:PC3 whole cell lysate(40ug)