产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

RhoBTB1/2 (T85) polyclonal antibody（KU）

货号: BS2503

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS2503

Product Name :RhoBTB1/2 (T85) polyclonal antibody（KU）

Swiss-Prot :Q9BYZ6/O94844

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :RHOBTB1 (Rho-related BTB domain-containing protein 1) and RHOBTB3 (Rho-related BTB domain-containing protein 3) each contain two BTB (POZ) domains and belong to the RhoBTB subfamily of Rho GTPases. Members of the RhoBTB subfamily are evolutionarily conserved and are characterized by a proline-rich region, a GTPase domain and two tandem BTB repeats. While both RHOBTB1 and RHOBTB3 are expressed ubiquitously, RHOBTB1 is found at high levels in placenta, stomach, testis, kidney and skeletal muscle, whereas RHOBTB3 is found at high levels in neural and cardiac tissues. RHOBTB1 is thought to play a role in GTPase-mediated signaling and may participate in organization of the Actin filament system. Additionally, RHOBTB1 expression is decreased in head and neck carcinomas, suggesting a possible role for RHOBTB1 as a tumor suppressor.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :RhoBTB1/2 (T85) polyclonal antibody detects endogenous levels of RhoBTB1/2 protein.

BiowMW :~ 83 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Rho-related BTB domain-containing protein 2; Deleted in breast cancer 2 gene protein; p83; RHOBTB2; DBC2; KIAA0717; Rho-related BTB domain-containing protein 1; RHOBTB1; KIAA0740

Immunogen :Synthetic peptide, corresponding to amino acids 52-98 of Human RhoBTB1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of RhoBTB1/2 (T85) pAb at 1:1000 dilution Lane1:The Kidney tissue lysate of Mouse(40ug) Lane2:The Kidney tissue lysate of Rat(40ug) Lane3:U-87MG whole cell lysate(40ug) Lane4:Hela whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of RhoBTB1/2 (T85) pAb in paraffin-embedded human tonsil carcinoma tissue at 1:50.