中国 EN 400-660-9091

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

TAF II p68 (N380) polyclonal antibody(KU)

货号: BS2499
价格 1140
货期 现货(1-2个工作日)
25ul 50ul 100ul 200ul
No. :BS2499
Product Name :TAF II p68 (N380) polyclonal antibody(KU)
Swiss-Prot :Q92804
Host :Rabbit
Reactivity :Human,Mouse,Rat
Applications :WB IHC
Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200
Background :TAF II p68, also known as TAF15, RBP56 or TAF2N, is a member of the RNA polymerase II multiprotein complex and is present in certain TFIID subcomplexes. Expressed throughout the body, TAF II p68 is a single stranded RNA binding protein that shares homology with TLS (translocated in liposarcoma) and EWS (Ewing's sarcoma), both of which are proto-oncogenes. Fusion of TAF II p68 with certain transcription factors transforms it into an oncoprotein with oncogenic potential at the N-terminus. When, for example, TAF II p68 is fused with TEC (translocated in extraskeletal chondrosarcoma), the fusion pair acts as an oncoprotein in which TAF II p68 is the transactivation domain. Defects in the gene encoding TAF II p68 are associated with extraskeletal myxoid chondrosarcoma, a malignant soft tumor.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :TAF II p68 (N380) polyclonal antibody detects endogenous levels of TAF II protein.
BiowMW :~ 68 kDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :TATA-binding protein-associated factor 2N; 68 kDa TATA-binding protein-associated factor; TAF(II)68; TAFII68; RNA-binding protein 56; TAF15; RBP56; TAF2N
Immunogen :Synthetic peptide, corresponding to amino acids 347-398 of Human TAF II p68.
Conjugate :Unconjugated
Modification :Unmodification
Western blot (WB) analysis of TAF II p68 (N380) pAb at 1:500 dilution Lane1:3T3-L1 whole cell lysate(40ug) Lane2:C6 whole cell lysate(40ug) Lane3:MCF-7 whole cell lysate(40ug) Lane4:HEK293T whole cell lysate(40ug)
Immunohistochemistry (IHC) analyzes of TAF II p68 (N380) pAb in paraffin-embedded human tonsil carcinoma tissue at 1:50.

关注我们

400-660-9091

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com