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TNF-IP 1 (S122) polyclonal antibody（KU）

货号: BS2484

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS2484

Product Name :TNF-IP 1 (S122) polyclonal antibody（KU）

Swiss-Prot :Q13829

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :TNFα-IP 1 (tumor necrosis factor, α-induced protein 1, endothelial), also known as B12, B61, EDP1 or TNFAIP1, is a BTB/POZ domain-containing protein that belongs to the KCTD10/KCTD13/TNFAIP1 family. TNFα-IP 1 contains one BTB/POZ motif, which is known to mediate homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. The expression of TNFα-IP 1 can be induced by IL-6 and by TNFα in the umbilical vein of endothelial cells. TNFα-IP 1 may be involved in DNA repair, DNA synthesis, cell apoptosis and human diseases. TNFα-IP 1 is suggested to play a role in the process of cancer and in the innate immunity against the Hepatitis B virus.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :TNF-IP 1 (S122) polyclonal antibody detects endogenous levels of TNF-IP 1 protein.

BiowMW :~ 36 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2; hBACURD2; BTB/POZ domain-containing protein TNFAIP1; Protein B12; Tumor necrosis factor, alpha-induced protein 1, endothelial; TNFAIP1; BACURD2; EDP1

Immunogen :Synthetic peptide, corresponding to amino acids 90-140 of Human TNF-IP 1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of TNF-IP 1 (S122) pAb at 1:500 dilution Lane1:A549 whole cell lysate(40ug) Lane2:Hela whole cell lysate(40ug) Lane3:PC12 whole cell lysate(40ug) Lane4:3T3-L1 whole cell lysate(40ug) Lane5:BV2 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of TNF-IP 1 (S122) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.