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UDG (H221) polyclonal antibody（KU）

货号: BS2465

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS2465

Product Name :UDG (H221) polyclonal antibody（KU）

Swiss-Prot :P13051

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :The human UNG-gene encodes nuclear (UNG2) and mitochondrial (UNG1) forms of uracil-DNA glycosylase using differentially regulated promoters, PA and PB, and alternative splicing to produce two proteins with unique N-terminal sorting sequences. Uracil in DNA may result from deamination of cytosine which can give rise to transition mutations. Uracil-DNA glycosylase is the DNA repair enzyme responsible for the removal of uracil from DNA. This is probably a biologically important function in the prevention of mutagenesis resulting from cytosine deamination. UNG2 removes misincorporated dUMP residues.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :UDG (H221) polyclonal antibody detects endogenous levels of UDG protein.

BiowMW :~ 35 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Uracil-DNA glycosylase; UDG; UNG; DGU; UNG1; UNG15

Immunogen :Synthetic peptide, corresponding to amino acids 200-240 of Human UDG.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of UDG (H221) pAb at 1:500 dilution Lane1:Hela whole cell lysate(40ug) Lane2:MCF-7 whole cell lysate(40ug) Lane3:SP2/0 whole cell lysate(40ug) Lane4:H9C2 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of UDG (H221) pAb in paraffin-embedded human skeletal muscle tissue.