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Stat5 (W287) polyclonal antibody（KU）

货号: BS2427

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS2427

Product Name :Stat5 (W287) polyclonal antibody（KU）

Swiss-Prot :P42229/P51692

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :Stat 5a protein is a transcription factor activated by hormone and cytokines. Two highly related, but distinct Stat 5 genes (Stat 5a and Stat 5b) were identified in mouse. The amino acid sequences of Stat 5a and Stat 5b show 96% sequence similarity, and both proteins are co expressed in most tissues of both virgin and lactating mice. However, differential accumulation of Stat 5a and Stat 5b mRNA has been reported for both muscle and mammary tissue. Stat 5a is critically involved in a variety of physiological functions, including reproduction, lactation, immune function and somatic growth.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Stat5 (W287) polyclonal antibody detects endogenous levels of Stat5 protein.

BiowMW :~ 90 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Immune Cell Signaling,Jak Stat ：IL-6 Receptor Signaling,T cell receptor signaling,

Alternative Name :Signal transducer and activator of transcription 5A; STAT5A; STAT5; Signal transducer and activator of transcription 5B; STAT5B

Immunogen :Synthetic peptide, corresponding to amino acids 250-300 of Human Stat5a.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Stat5 (W287) pAb at 1:500 dilution Lane1:PC3 whole cell lysate(40ug) Lane2:MCF-7 whole cell lysate(40ug) Lane3:Hela whole cell lysate(40ug) Lane4:SK-OVCAR3 whole cell lysate(40ug) Lane5:A549 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of Stat5 (W287) pAb in paraffin-embedded human tonsil carcinoma tissue at 1:50.

MicroRNA‐146b, a Sensitive Indicator of Mesenchymal Stem Cell Repair of Acute Renal Injury

JournalStem Cells Translational Medicine

ApplicationWB

IF5.962

SpeciesRat

PMID27400799