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ILKAP (K71) polyclonal antibody（KU）

货号: BS2359

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS2359

Product Name :ILKAP (K71) polyclonal antibody（KU）

Swiss-Prot :Q9H0C8

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Background :ILKAP (integrin-linked kinase-associated serine/threonine phosphatase 2C),also known as PP2Cδ, is a 392 amino acid cytoplasmic protein phosphatase that selectively interacts with integrin linked kinase (ILK) to regulate growth factor signaling and cell adhesion. While widely expressed, ILKAP is found at highest levels in striated muscle with lower levels found in smooth muscle.ILKAP belongs to the PP2C family and contains one PP2C-like domain. ILKAP has been suggested to inhibit oncogenic transformation and the ILK-GSK3βsignaling axis, and can bind two magnesium or manganese ions per subunit as cofactors. The gene encoding ILKAP maps to human chromosome 2,which consists of 237 million bases encoding over 1,400 genes and making up approximately 8% of the human genome.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :he antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :LKAP (K71)pAb detects endogenous levels of ILKAP protein.

BiowMW :~ 45 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Integrin-linked kinase-associated serine/threonine phosphatase 2C; ILKAP; ILKAP

Immunogen :Synthetic peptide, corresponding to amino acids 40-90 of Human ILKAP.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of ILKAP (K71) polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:sp2/0 whole cell lysate Lane3:H9C2 whole cell lysate

Immunohistochemistry (IHC) analyzes of ILKAP (K71) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.