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PBF (R151) polyclonal antibody（KU）

货号: BS2285

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS2285

Product Name :PBF (R151) polyclonal antibody（KU）

Swiss-Prot :P53801

Host :Rabbit

Reactivity :Human

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :PBF, also known as PTTG1IP (pituitary tumor-transforming 1 interacting protein), is a 180 amino acid single-pass type I membrane protein that localizes both the cytoplasm and the nucleus and contains a coiled-coil domain. Expressed ubiquitously, PBF interacts with PTTG and is thought to facilitate the nuclear translocation of PTTG, thereby allowing the PTTG-dependent transcriptional activation of fibroblast growth factor (FGF). The gene encoding PBF maps to human chromosome 21, which houses approximately 300 genes and comprises nearly 1.5% of the human genome. Chromosome 21-associated disorders include Alzheimer’s disease, amyotrophic lateral sclerosis and, most notably, Down syndrome (also known as trisomy 21).

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :PBF (R151) polyclonal antibody detects endogenous levels of PBF protein.

BiowMW :~ 22 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PTTG binding factor; PTTG-binding factor; PTTG; Pttg1ip; PBF; PTTG1IP

Immunogen :Synthetic peptide, corresponding to amino acids 130-180 of Human PBF.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of PBF (R151) pAb at 1:500 dilution Lane1:Panc1 whole cell lysate(40ug) Lane2:SGC7901 whole cell lysate(40ug) Lane3:A375 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of PBF (R151) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.