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TIS11D (H243) polyclonal antibody（KU）

货号: BS2278

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS2278

Product Name :TIS11D (H243) polyclonal antibody（KU）

Swiss-Prot :P47974

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :TIS11D, also known as ZFP36LA (zinc finger protein 36, C3H type-like 2), BRF2 (butyrate response factor 2), ERF2 or RNF162C, is a 494 amino acid protein that localizes to the nucleus and contains two CSH1-type zinc fingers. Belonging to the TIS11 family of early response proteins, TIS11D is thought to function as a nuclear transcription factor that binds to 5'UUAUUUAUUU-3' core RNA sequences and may regulate growth factor-induced cellular responses. The gene encoding TIS11D maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :TIS11D (H243) polyclonal antibody detects endogenous levels of TIS11D protein.

BiowMW :~ 57 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Zinc finger protein 36, C3H1 type-like 2; ZFP36-like 2; Butyrate response factor 2; EGF-response factor 2; ERF-2; Protein TIS11D; ZFP36L2; BRF2; ERF2; RNF162C; TIS11D

Immunogen :Synthetic peptide, corresponding to amino acids 200-250 of Human TIS11D.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of TIS11D (H243) polyclonal antibody at 1:500 dilution Lane1:PC12 whole cell lysate(40ug) Lane2:HCT116 whole cell lysate(40ug) Lane3:CT26 whole cell lysate(40ug) Lane4:A375 whole cell lysate(40ug) Lane5:Myla2059 whole cell lysate(40ug)