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PFKFB1 (E442) polyclonal antibody

货号: BS2259

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS2259

Product Name :PFKFB1 (E442) polyclonal antibody

Swiss-Prot :P16118

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :PFK-1 undergoes activation in the presence of elevated AMP. The most potent activator is fructose-2,6-bisphosphate, which is produced by PFK-2 from the same substrate, fructose 6-phosphate. PFK-2 is bifunctional and a key regulator for PFK-1. PFK-2 catalyzes the synthesis of fructose-2,6-bisphosphate, and contains fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. PFK-2 is dimeric and isoenzymes include PFK-2 liver (PFKFB1, PFRX), PFK-2 cardiac (PFKFB2), PFK-2 placental (PFKFB3, inducible PFK-2) and PFK-2 testis (PFKFB4).

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :PFKFB1 (E442) polyclonal antibody detects endogenous levels of PFKFB1 protein.

BiowMW :~ 55 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :PFK-2 liver; PFKFB1; PFRX; F6PK; 6PF-2-K/Fru-2; 6-P2ASE liver isozyme; 6-phosphofructo-2-kinase/fructose-2; 6-biphosphatase 1;

Immunogen :Synthetic peptide, corresponding to amino acids 410-460 of Human PFKFB1.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of PFKFB1 (E442) polyclonal antibody in extracts from hela cells.

Immunohistochemistry (IHC) analyzes of PFKFB1 (E442) pAb in paraffin-embedded human liver carcinoma tissue at 1:100.

免疫沉淀（IP）

免疫组织化学（IHC）