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CDH13 (M352) polyclonal antibody

货号: BS2219

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS2219

Product Name :CDH13 (M352) polyclonal antibody

Swiss-Prot :P55290

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Background :The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including β-catenin, to regulate cadherin function. T-cadherin (for truncated-cadherin, also designated heartcadherin or cadherin-13) expression levels have been shown to be reduced in human breast cancers and carcinoma cells lines. Evidence suggests that

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :CDH13 (M352) polyclonal antibody detects endogenous levels of CDH13 protein.

BiowMW :78,105,130kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :CAD13; Cadherin-13; CDH13; CDHH; H-cadherin; Heart Cadherin; P105; T cad; T Cadherin; T-cad; T-cadherin; Truncated Cadherin;

Immunogen :Synthetic peptide, corresponding to amino acids 330-380 of Human CDH13.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of CDH13 (M352) polyclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate(40ug) Lane2:H9C2 whole cell lysate(40ug) Lane3:NIH-3T3 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of CDH13 (M352) pAb in paraffin-embedded human tonsil cancer tissue at 1:50.