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Cox-4 (A37) polyclonal antibody（KU）

货号: BS2186

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS2186

Product Name :Cox-4 (A37) polyclonal antibody（KU）

Swiss-Prot :P13073

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :Cytochrome c oxidase (COX) functions as the terminal oxidase of the respiratory chain that uses cytochrome c as an electron donor to drive a proton gradient across the inner mitochondrial membrane. The mammalian COX apoenzyme is a heteromer consisting of three mitochondrial encoded catalytic subunits and several nuclear gene encoded structural subunits. COX contains two iron-coordination sites and two copper-coordination sites. Cytochrome c oxidase IV (COX4) is a nuclear-encoded subunit of COX that may play a role in regulating COX activity. COX4 is expressed ubiquitously in adult human tissue with the strongest levels of expression in the pancreas and moderate expression levels in heart, skeletal muscle and placenta.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Cox-4 (A37) polyclonal antibody detects endogenous levels of Cox-4 protein

BiowMW :~ 20 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :AMPK Signaling Pathway,

Alternative Name :Cytochrome c oxidase subunit 4 isoform 1, mitochondrial; Cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit IV isoform 1; COX IV-1; COX4I1; COX4

Immunogen :Synthetic peptide, corresponding to the N-terminus of Human Cox-4.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Cox-4 (A37) polyclonal antibody at 1:500 dilution Lane1:K562 whole cell lysate(40ug) Lane2:HepG2 whole cell lysate(40ug) Lane3:HEK293T whole cell lysate(40ug) Lane4:LO2 whole cell lysate(40ug) Lane5:A549 whole cell lysate(40ug) Lane6:C6 whole cell lysate(40ug) Lane7:AML-12 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of Cox-4 (A37) pAb in paraffin-embedded human colon carcinoma tissue.

Endoplasmic Reticulum Stress Mediates Methamphetamine-Induced Blood–Brain Barrier Damage

JournalFrontiers in Pharmacology

ApplicationWB

IF3.845

SpeciesMouse

PMID28959203
Sodium Butyrate Ameliorates High-Fat-Diet-Induced Non-alcoholic Fatty Liver Disease through Peroxisome Proliferator-Activated Receptor α-Mediated Activation of β Oxidation and Suppression of Inflammation

JournalJournal Of Agricultural And Food Chemistry

ApplicationWB

IF4.192

SpeciesRat

PMID29961332