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SLK polyclonal antibody（KU）

货号: BS2137

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS2137

Product Name :SLK polyclonal antibody（KU）

Swiss-Prot :Q9H2G2

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :SLK (Ste20-like kinase), also known as STK2 (serine/threonine protein kinase 2) or se20-9, is a member of the serine/threonine kinase subfamily, Ste20. This subfamily is comprised of several mammalian kinases which exhibit sequence similarity to the Saccharomyces cerevisiae serine/threonine kinase Ste20, a protein involved in relaying signals from G protein-coupled receptors to cytosolic MAP kinase cascades. Members of this subfamily include KHS, GLK, YSK1, HPK1, Krs-1, Krs-2, GC kinase, HGK and SLK. SLK is a ubiquitously expressed protein that localizes to the cytoplasm and contains an N-terminal protein kinase domain, a central coiled-coil domain and a C-terminal ATH domain. SLK is activated through cleavage by caspase-3. SLK indirectly associates with microtubules and plays an important role in cellular stress, cell motility, cell death and cytoskeletal dynamics.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :SLK polyclonal antibody detects endogenous levels of SLK protein.

BiowMW :~ 220 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :STE20-like serine/threonine-protein kinase; STE20-like kinase; hSLK; CTCL tumor antigen se20-9; STE20-related serine/threonine-protein kinase; STE20-related kinase; Serine/threonine-protein kinase 2; SLK; KIAA0204; STK2

Immunogen :Synthetic peptide, corresponding Human SLK.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of SLK polyclonal antibody at 1:500 dilution Lane1:HCT116 whole cell lysate(40ug) Lane2:THP-1 whole cell lysate(20ug) Lane3:The Heart tissue lysate of Rat(40ug) Lane4:The Heart tissue lysate of Mouse(40ug) Lane5:LOVO whole cell lysate(20ug)