Product Name :PFKFB1/4 (E349) polyclonal antibody（KU）
Swiss-Prot :P16118/Q16877
Reactivity :Human,Mouse,Rat
Application_all :WB: 1:500~1:1000
Background :PFK-1 undergoes activation in the presence of elevated AMP. The most potent activator is fructose-2,6-bisphosphate, which is produced by PFK-2 from the same substrate, fructose 6-phosphate. PFK-2 is bifunctional and a key regulator for PFK-1. PFK-2 catalyzes the synthesis of fructose-2,6-bisphosphate, and contains fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. PFK-2 is dimeric and isoenzymes include PFK-2 liver (PFKFB1, PFRX), PFK-2 cardiac (PFKFB2), PFK-2 placental (PFKFB3, inducible PFK-2) and PFK-2 testis (PFKFB4).
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :PFKFB1/4 (E349) polyclonal antibody detects endogenous levels of PFKFB1/4 protein.
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :PFK-2 liver; PFKFB1; PFRX; F6PK; 6PF-2-K/Fru-2; 6-P2ASE liver isozyme; 6-phosphofructo-2-kinase/fructose-2; 6-biphosphatase 1; PFK-2 testis; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4; 6PF-2-K/Fru-2,6-P2ase 4; PFK/FBPase 4; 6PF-2-K/Fru-2,6-P2ase testis-type isozyme; 6-phosphofructo-2-kinase; Fructose-2,6-bisphosphatase; PFKFB4
Immunogen :Synthetic peptide, corresponding to amino acids 320-370 of Human PFKFB1.
Modification :Unmodification
