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TDE1 (R392) polyclonal antibody

货号: BS2051

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS2051

Product Name :TDE1 (R392) polyclonal antibody

Swiss-Prot :Q13530

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :IHC

Application_all :IHC: 1:50~1:200

Background :TDE1, tumor differentially expressed protein 1, is a multi-pass membrane protein also known as serine incorporator 3. Also found on the membranes of the Golgi apparatus within cells, TDE1 is highly expressed in neuronal populations but is also found in thymus, kidney, liver and testis. Expression levels of TDE1 in tumors can be as much as tenfold the amount found in normal tissue of the same type. This increased expression implicates TDE1 as being involved in the cellular transformation from normal to malignant tissue. It is believed TDE1 contributes to oncogenesis by partially protecting cells from serum starvation and etoposide-induced apoptosis. The mechanism through which TDE1 protects cells is poorly understood, but may involve aberrant methylation of TDE1 complexes.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :TDE1 (R392) polyclonal antibody detects endogenous levels of TDE1 protein.

BiowMW :~ 53 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Serine incorporator 3; Tumor differentially expressed protein 1; SERINC3; DIFF33; TDE1; SBBI99

Immunogen :Synthetic peptide, corresponding to amino acids 360-412 of Human TDE1.

Conjugate :Unconjugated

Modification :Unmodification

Immunohistochemistry (IHC) analyzes of TDE1 (R392) pAb in paraffin-embedded human tonsil carcinoma tissue at 1:50.

免疫沉淀（IP）

免疫组织化学（IHC）

免疫荧光（IF）