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TRAIL (S63) polyclonal antibody

货号: BS2007

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BS2007

Product Name :TRAIL (S63) polyclonal antibody

Swiss-Prot :P50591

Host :Rabbit

Reactivity :Human

Applications :IHC IF

Application_all :IHC: 1:50~1:200 IF: 1:50~1:200

Background :Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL), also referred to as Apo2 ligand, first identified based on its sequence homology to TNF and Fas/Apo ligand is a member of the TNF family of cytokines and either exists as a type II membrane or soluble protein. TRAIL induces apoptosis in a variety of transformed cell lines and plays a role in anti-tumor and anti-viral immune surveillance. TRAIL signals via binding with death receptors DR4 (TRAIL-R1) (4) and DR5 (TRAIL-R2) which can trigger apoptosis as well as NF-κB activation.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :TRAIL (S63) polyclonal antibody detects endogenous levels of TRAIL protein.

BiowMW :~34 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Death Receptor Signaling,

Alternative Name :TNF-related apoptosis-inducing ligand; Protein TRAIL; Apo-2 ligand; Apo-2L; CD253 antigen; TRAIL; 8743; TNFSF10; 603598; P50591; APO2L; Apo-2L; TL2; TRAIL;

Immunogen :Synthetic peptide, corresponding to amino acids 50-100 of Human TRAIL.

Conjugate :Unconjugated

Modification :Unmodification

Immunohistochemistry (IHC) analyzes of TRAIL (S63) pAb in paraffin-embedded human breast carcinoma tissue at 1:50.showing Cell membrane staining. Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.

Immunohistochemistry (IHC) analyzes of TRAIL (S63) pAb in paraffin-embedded human lung carcinoma tissue at 1:50.showing Cell membrane staining. Negative control (the right)Using PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG-biotin followed by avidin-peroxidase.