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Stat5a (S420) polyclonal antibody

货号: BS1995

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS1995

Product Name :Stat5a (S420) polyclonal antibody

Swiss-Prot :P42229

Host :Rabbit

Reactivity :Human,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1000 IHC: 1:50~1:200 IF: 1:50~1:200

Background :Stat 5a protein is a transcription factor activated by hormone and cytokines. Two highly related, but distinct Stat 5 genes (Stat 5a and Stat 5b) were identified in mouse. The amino acid sequences of Stat 5a and Stat 5b show 96% sequence similarity, and both proteins are co expressed in most tissues of both virgin and lactating mice. However, differential accumulation of Stat 5a and Stat 5b mRNA has been reported for both muscle and mammary tissue. Stat 5a is critically involved in a variety of physiological functions, including reproduction, lactation, immune function and somatic growth.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Stat5a (S420) polyclonal antibody detects endogenous levels of Stat5a protein.

BiowMW :~ 90 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Immune Cell Signaling,Jak Stat ：IL-6 Receptor Signaling,T cell receptor signaling,

Alternative Name :Signal transducer and activator of transcription 5A; STAT5A; STAT5

Immunogen :Synthetic peptide, corresponding to amino acids 400-450 of Human Stat5a.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of STAT5A pAb at 1:500 dilution Lane1:SP2/0 whole cell lysate(40ug) Lane2:SHSY5Y whole cell lysate(40ug) Lane3:MCF-7 whole cell lysate(40ug)

Oncostatin M receptor β deficiency attenuates atherogenesis by inhibiting JAK2/STAT3 signaling in macrophages

JournalJournal Of Lipid Research

ApplicationWB

IF4.483

SpeciesMouse

PMID28258089