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Creatine Kinase M (Y14) polyclonal antibody（KU）

货号: BS1915

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS1915

Product Name :Creatine Kinase M (Y14) polyclonal antibody（KU）

Swiss-Prot :P06732

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Background :Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa. The CKM isoform, predominant in skeletal muscle and heart tissue, is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. CKM reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Creatine Kinase M (Y14) polyclonal antibody detects endogenous levels of Creatine Kinase M protein.

BiowMW :~ 43 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :M-CK; CKMM; Creatine kinase M-type; Creatine kinase M chain; CKM; CK-M; MCK

Immunogen :Synthetic peptide, corresponding to the N-terminus of Human Creatine Kinase M.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Creatine Kinase M (Y14) polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate Lane2:NIH-3T3 cell lysate Lane3:H9C2 cell lysate

Immunohistochemistry (IHC) analyzes of Creatine Kinase M (Y14) pAb in paraffin-embedded human tonsil carcinoma tissue at 1:50.

Efficient and Reproducible Myogenic Differentiation from Human iPS Cells: Prospects for Modeling Miyoshi Myopathy In Vitro

JournalPLoS One

ApplicationIHC,WB

IF3.24

SpeciesHuamn

PMID23626698