产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

SAPAP1 (E817) polyclonal antibody（KU）

货号: BS1864

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS1864

Product Name :SAPAP1 (E817) polyclonal antibody（KU）

Swiss-Prot :O14490

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Background :Members of the postsynaptic density-95 (PSD-95)/SAP90 family of membraneassociated guanylate kinase (MAGUK) proteins function as multimodular scaffolds that organize protein-signaling complexes at neuronal synapses. PSD-95/SAP90 binds guanylate kinase-associated protein (GKAP), also designated GK domain-binding protein, DAP-1-α, DAP-1-β, PSD-95 binding protein, PSD-95/SAP90 associated protein, or SAPAP1, through the guanylate kinase domain. SAPAP1 is expressed widely in neurons of the cortex and hippocampus and in the Purkinje and granule cells of the cerebellum. N-terminal splice variants of SAPAP1 are expressed as 95 and 130 kDa proteins. SAPAP1 is localized specifically in the PSD of glutamatergic synapses, consistent with its direct interaction with PSD-95 family proteins.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :SAPAP1 (E817) polyclonal antibody detects endogenous levels of SAPAP1 protein.

BiowMW :~ 108 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Disks large-associated protein 1; DAP-1; Guanylate kinase-associated protein; hGKAP; PSD-95/SAP90-binding protein 1; SAP90/PSD-95-associated protein 1; SAPAP1; DLGAP1; DAP1; GKAP

Immunogen :Synthetic peptide, corresponding to amino acids 791-840 of Human SAPAP1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of SAPAP1 (E817) polyclonal antibody at 1:500 dilution Lane1:The Brain tissue lysate of Mouse(40ug) Lane2:The Brain tissue lysate of Rat(40ug) Lane3:U-87MG whole cell lysate(40ug) Lane4:U-251MG whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of SAPAP1 (E817) pAb in paraffin-embedded human brain carcinoma tissue at 1:50.