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Ku-70 (S1) polyclonal antibody（KU）

货号: BS1818

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS1818

Product Name :Ku-70 (S1) polyclonal antibody（KU）

Swiss-Prot :P12956

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :The Ku protein is localized in the nucleus and is composed of subunits referred to as Ku-70 (or p70) and Ku-86 (or p86), which is also known by the synonym Ku-80 (or p80). Ku was first described as an autoantigen to which antibodies were produced in a patient with scleroderma-polymyositis overlap syndrome, and was later found in the sera of patients with other rheumatic diseases. Both subunits of the Ku protein have been cloned, and a number of functions have been proposed for Ku, including cell signaling, DNA replication and transcriptional activation.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Ku70 (S1) polyclonal antibody detects endogenous levels of Ku70 protein.

BiowMW :~ 70 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :X-ray repair cross-complementing protein 6; 5'-deoxyribose-5-phosphate lyase Ku70; 5'-dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; CTC box-binding factor 75 kDa subunit; CTC75; CTCBF; DNA repair protein XRCC6; Lupus Ku autoantigen protein p70; Ku70; Thyroid-lupus autoantigen; TLAA; X-ray repair complementing defective repair in; Chinese hamster cells 6; XRCC6; G22P1

Immunogen :Synthetic peptide, corresponding to the N-terminus of Human Ku-70.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Ku-70 (S1) pAb at 1:500 dilution Lane1:MCF-7 whole cell lysate(2.5ug) Lane2:HEK293T whole cell lysate(2.5ug) Lane3:PC12 whole cell lysate(20ug) Lane4:The Kidney tissue lysate of Mouse(40ug) Lane5:AML-12 whole cell lysate(40ug) Lane6:3T3-L1 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of Ku-70 (S1) pAb in paraffin-embedded liver cancer tissue at 1:100.