产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

SSB (T362) polyclonal antibody（KU）

货号: BS1770

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS1770

Product Name :SSB (T362) polyclonal antibody（KU）

Swiss-Prot :P05455

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :Ro/SSA is a ribonucleoprotein that binds to autoantibodies in 35 to 50% of patients with SLE and in up to 97% of patients with Sjogren syndrome. The Ro/SSA particle consists of a single immunoreactive protein noncovalently bound with one of four small RNA molecules. Most anti-Ro/SSA-positive sera have antibodies not only against the immunoreactive protein, but also against an Ro/SSA protein. The genes which encode the two proteins map to human chromosomes 11p15.5 and 1q31, respectively. La/SSB is an autoimmune RNA-binding protein that plays a role in the transcription of RNA polymerase III was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome and SLE.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :SSB (T362) polyclonal antibody detects endogenous levels of SSB protein.

BiowMW :~50 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Autoantigen La; La; La autoantigen; La autoantigen homolog; La protein; La ribonucleoprotein; La ribonucleoprotein domain family member 3; LA; LARP3; Lupus La antigen; Lupus La protein; Lupus La protein homolog; MGC118101; MGC93380; mRNA for autoantigen; OTTMUSP00000014043; RP23 273G23.1; Sjoegren syndrome type B antigen; Sjoegren syndrome type B antigen; Sjogren syndrome antigen B (autoantigen La); Sjogren syndrome antigen B; SS B; SS-B; SS-B/La protein; SSB;

Immunogen :Synthetic peptide, corresponding to amino acids 331-380 of Human SSB.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of SSB (T362) pAb at 1:1000 dilution Lane1:A2780 whole cell lysate(20ug) Lane2:PC3 whole cell lysate(20ug) Lane3:L02 whole cell lysate(20ug) Lane4:The Ovary tissue lysate of Rat(40ug) Lane5:AML-12 whole cell lysate(40ug) Lane6:3T3-L1 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of SSB (T362) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.