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RPA2 (A17) polyclonal antibody（KU）

货号: BS1692

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

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No. :BS1692

Product Name :RPA2 (A17) polyclonal antibody（KU）

Swiss-Prot :P15927

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB IHC IF

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Background :RPA is a major damage-recognition protein involved in the early stages of nucleotide excision repair. It can also play a role in telomere maintenance. The C-terminus of RPA 32 can specfically intereact with the DNA repair enzyme UNG2 and repair factors XPA and Rad52, each of which functions in a different repair pathway. In addition, RPA 32 binds specifically to the SH2 domain of Stat3 in vivo, and overexpression of RPA 32 corresponds to the augmented growth factor-stimulated tyrosine phosphorylation and transcription activities of Stat3.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :RPA2 (A17) polyclonal antibody detects endogenous levels of RPA2 protein.

BiowMW :~ 32 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Replication protein A 32 kDa subunit; RP-A p32; RF-A protein 2; RPA2; REPA2; RPA32; RPA34

Immunogen :Synthetic peptide, corresponding to the N-terminus of Human RPA2.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of RPA2 (A17) pAb at 1:500 dilution Lane1:H1792 whole cell lysate(40ug) Lane2:EC9706 whole cell lysate(40ug) Lane3:A549 whole cell lysate(40ug) Lane4:SGC7901 whole cell lysate(40ug) Lane5:HCT116 whole cell lysate(40ug) Lane6:PMVEC whole cell lysate(40ug) Lane7:3T3-L1 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of RPA2 (A17) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.