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Sox9 (Q175) polyclonal antibody

货号: BS1597

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS1597

Product Name :Sox9 (Q175) polyclonal antibody

Swiss-Prot :P48436

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Background :Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :SOX-9 (Q175) polyclonal antibody detects endogenous levels of SOX-9 protein.

BiowMW :~ 56 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Contribution of Soluble Factors to EMT,

Alternative Name :Transcription factor SOX-9; SOX9;

Immunogen :Synthetic peptide, corresponding to amino acids 150-200 of Human Sox9.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Sox9 (Q175) polyclonal antibody at 1:500 dilution Lane1:C6 whole cell lysate(40ug) Lane2:BV2 whole cell lysate(40ug) Lane3:Hela whole cell lysate(40ug) Lane4:Panc1 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of Sox9 (Q175) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.

Peroxisome Proliferator-Activated Receptor-γ Coactivator-1α Inhibits Vascular Calcification Through Sirtuin 3-Mediated Reduction of Mitochondrial Oxidative Stress

JournalAntioxidants & Redox Signaling

ApplicationWB

IF5.828

SpeciesRat

PMID30829051
The IRF1/GBP5 axis promotes osteoarthritis progression by activating chondrocyte pyroptosis

JournalJournal of Orthopaedic Translation

ApplicationWB

IF6.6

SpeciesMouse

PMID