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Ubiquitin (A46) polyclonal antibody

货号: BS1487

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS1487

Product Name :Ubiquitin (A46) polyclonal antibody

Swiss-Prot :P62988

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :Ubiquitin (Ub) is among the most phylogenetically conserved proteins known. The primary function of ubiquitin is to clear abnormal, foreign and improperly folded proteins by targeting them for degradation by the 26S proteosome. This small, 76 amino acid protein can be covalently attached to cellular proteins via an isopeptide linkage between the carboxy terminal group of ubiquitin and lysine amino groups on the acceptor protein. For proteolysis to occur, ubiquitin oligomers must be assembled. Ubiquitin chains on proteolytic substrates are commonly found to have an isopeptide bridge between Lysine 48 of one ubiquitin molecule and the carboxy-terminus of a neighboring ubiquitin molecule.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Ubiquitin (A46) polyclonal antibody detects ubiquitin, polyubiquitin and ubiquitinated proteins.

BiowMW :~ *8 kDa or Uncertain

Note :For research use only, not for use in diagnostic procedure.

Pathway :Ubiquitin Proteasome,

Alternative Name :Polyubiquitin B; RPS 27A; RPS27A; UBA 52; UBA 80; UBA52; UBA80; UBB; UBC; UBCEP 1; UBCEP 2; UBCEP1; UBCEP2; Ubiquitin; ubiquitin B

Immunogen :Synthetic peptide, corresponding to amino acids 20-60 of Ubiquitin.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Ubiquitin (A46) polyclonal antibody at 1:500 dilution Lane1:Hela cell lysate treated with UV Lane2:HEK293T cell ysate Lane3:NIH-3T3 cell lysate treated with UV Lane4:Rat kidney tissue lysate

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