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SENP6 (K1077) polyclonal antibody

货号: BS1473

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS1473

Product Name :SENP6 (K1077) polyclonal antibody

Swiss-Prot :Q9GZR1

Host :Rabbit

Reactivity :Human, Mouse, Rat

Applications :WB IHC

Application_all :WB:1:500~1:1000 IHC: 1:50~1:200

Background :SUMO (small ubiquitin-related modifier), a member of the ubiquitin-like protein family, regulates diverse cellular functions of a variety of target proteins including transcription, DNA repair, nucleocytoplasmic trafficking and chromosome segregation. SUMO precursor proteins undergo cleavage of the residues after the “GG” region by SUMO-specific proteases in maturation. This cleavage of the precursor is a prerequisite for subsequent sumoylation. The sentrin-specific (or SUMO-specific) protease (SENP) proteins belong to the peptidase C48 family and include SENP1-3 and SENP5-8. SENP1, SENP2 and SENP3 degrade UBL1 and SMT3H2 conjugates and subsequently release the monomers from sumoylated substrates.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :SENP6 (K1077) polyclonal antibody detects endogenous levels of SENP6 protein.

BiowMW :~ 126 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Sentrin-specific protease 6; SUMO-1-specific protease 1; Sentrin/SUMO-specific protease SENP6; KIAA0797; SSP1; SUSP1; FKSG6

Immunogen :Synthetic peptide, corresponding to amino acids 1040-1089 of Human SENP6.

Conjugate :Unconjugated

Modification :Unmodified

Western blot analysis of SENP6 expression in A2780 (A), HEK293T (B) whole cell lysates.

Immunohistochemistry (IHC) analyzes of SENP6 (K1077) pAb in paraffin-embedded human lung carcinoma tissue.

免疫沉淀（IP）

免疫组织化学（IHC）