中国 EN 400-660-9091

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

Lamin A/C (R386) polyclonal antibody(KU)

货号: BS1446
价格 1140
货期 现货(1-2个工作日)
25ul 50ul 100ul 200ul
No. :BS1446
Product Name :Lamin A/C (R386) polyclonal antibody(KU)
Swiss-Prot :P02545
Host :Rabbit
Reactivity :Human,Mouse,Rat
Applications :WB IHC IF
Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
Background :A unique family of cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed CED-3/ICE, functions as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Nuclear lamins are critical to maintaining the integrity of the nuclear envelope and cellular morphology.
Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity :Lamin A/C (R386) polyclonal antibody detects endogenous levels of Lamin A/C protein.
BiowMW :~ 74, 65 kDa
Note :For research use only, not for use in diagnostic procedure.
Alternative Name :Prelamin-A/C; Lamin-A/C; Lamin A/C; LaminA/C; 70 kDa lamin; Renal carcinoma antigen NY-REN-32; LMNA; LMN1; Lamin A; LaminA; Lamin-A; Lamin C; LaminC; Lamin-C
Immunogen :Synthetic peptide, corresponding to amino acids 351-400 of Human Lamin A/C.
Conjugate :Unconjugated
Modification :Unmodification
Western blot (WB) analysis of Lamin A/C (R386) polyclonal antibody at 1:500 dilution Lane1:HepG2 whole cell lysate(40ug) Lane2:L02 whole cell lysate(40ug) Lane3:PC12 whole cell lysate(40ug) Lane4:AML-12 whole cell lysate(40ug) Lane5:A549 whole cell lysate(40ug)
Immunohistochemistry (IHC) analyzes of Lamin A/C (R386) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.
  • Mitochondrial cristae architecture protects against mtDNA release and inflammation
    JournalCell Reports
    ApplicationIF
    IF9.995
    SpeciesHuman
  • Dimethyl fumarate attenuates cholestatic liver injury by activating the NRF2 and FXR pathways and suppressing NLRP3/GSDMD signaling in mice
    JournalEXPERIMENTAL CELL RESEARCH
    ApplicationWB
    IF3.7
    SpeciesMouse
  • Lipid synthesis, triggered by PPARγ T166 dephosphorylation, sustains reparative function of macrophages during tissue repair
    JournalNature Communications
    ApplicationWB
    IF14.7
    SpeciesMouse
  • Dietary Zn proteinate with moderate chelation strength alleviates heat stress-induced intestinal barrier function damage by promoting expression of tight junction proteins via the A20/NF-κB p65/MMP-2 pathway in the jejunum of broilers
    JournalJournal of Animal Science and Biotechnology
    ApplicationWB
    IF6.3
    SpeciesChicken
  • Microvesicle-Shuttled microRNA-130b Activates the Hepatic Inflammation by Inhibiting Glucocorticoid-Receptor-Mediated Immunosuppression in High-Fat Diet-Induced Obese Mice
    Journal10.3390/vetsci11110565
    ApplicationWB
    IF2
    SpeciesMouse

关注我们

400-660-9091

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com