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Tau (V398) polyclonal antibody（KU）

货号: BS1358

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS1358

Product Name :Tau (V398) polyclonal antibody（KU）

Swiss-Prot :P10636

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :Tau, also known as MAPT (microtubule-associated protein tau), MAPTL, MTBT1 or TAU, is a 758 amino acid protein that localizes to the cytoplasm, as well as to the cytoskeleton and the cell membrane, and contains four Tau/MAP repeats. Expressed in neuronal tissue and existing as multiple alternatively spliced isoforms, Tau functions to promote microtubule assembly and stability and is thought to be involved in the maintenance of neuronal polarity. Tau may also link microtubules with neural plasma membrane components and, addition to its role in microtubule stability, is also necessary for cytoskeletal plasticity.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Tau (V398) polyclonal antibody detects endogenous levels of Tau protein

BiowMW :50 to 80 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Neuronal and Glial Cell Marker Atlas,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,

Alternative Name :Microtubule-associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau; MAPT; MAPTL; MTBT1; TAU

Immunogen :Synthetic peptide, corresponding to amino acids 371-420 of Human Tau.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Tau (V398) polyclonal antibody at 1:500 dilution Lane1:The Brain tissue lysate of Rat(40ug) Lane2:The Brain tissue lysate of Mouse(40ug)

Gut commensal Agathobacter rectalis alleviates microglia-mediated neuroinflammation against pathogenesis of Alzheimer’s disease

Journal10.1016/j.isci.2024.111116

ApplicationWB

IF4.6

SpeciesMouse

PMID39498309