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Synuclein-β (S118) polyclonal antibody（KU）

货号: BS1348

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS1348

Product Name :Synuclein-β (S118) polyclonal antibody（KU）

Swiss-Prot :Q16143

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IF

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200

Background :The synuclein family members, including α-synuclein (also designated NACP for non-β amyloid component) and β-synuclein, are predominantly expressed in the brain and are speculated to be involved in synaptic regulation and neuronal plasticity. α-synuclein is localized to neuronal cell bodies and synapses. α-synuclein was first identified as a component of Alzheimer’s disease amyloid plaques. Abnormal platelet function in Alzheimer’s disease has been demonstrated. During megakaryocytic differentiation α-synuclein was found to be upregulated, while β-synuclein is downregulated, indicating that coordinate expression of synucleins may be important during hematopoetic cell differentiation. A mutant form of α-synuclein has been found in patients with early onset Parkinson’s disease.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Synuclein β (S118) polyclonal antibody detects endogenous levels of Synuclein β protein.

BiowMW :~ 19 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Beta-synuclein; SNCB; Synuclein β; β-Synuclein

Immunogen :Synthetic peptide, corresponding to amino acids 82-140 of Human Synuclein-β.

Conjugate :Unconjugated

Modification :Unmodified

Western blot (WB) analysis of Synuclein-β (S118) pAb at 1:500 dilution Lane1:The Brain tissue lysate of Mouse(20ug) Lane2:The Brain tissue lysate of Rat(40ug)

Immunohistochemistry (IHC) analyzes of Synuclein-β (S118) pAb in paraffin-embedded human breast carcinoma tissue at 1:50.