产品类别

联系我们

电话:025-68037686

地址:江苏生命科技创新园F6幢1层

订购:nanjing03@biogot.com

服务:biorase01@biogot.com

合作:lvyun@biogot.com

支持:may@biogot.com

Stat5a/b (A688) polyclonal antibody（KU）

货号: BS1338

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

抗体定制服务咨询

说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS1338

Product Name :Stat5a/b (A688) polyclonal antibody（KU）

Swiss-Prot :P42229/P51692

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB IF

Application_all :WB:1:500~1:1000 IF: 1:50~1:200

Background :Stat 5a protein is a transcription factor activated by hormone and cytokines. Two highly related, but distinct Stat 5 genes (Stat 5a and Stat 5b) were identified in mouse. The amino acid sequences of Stat 5a and Stat 5b show 96% sequence similarity, and both proteins are co expressed in most tissues of both virgin and lactating mice. However, differential accumulation of Stat 5a and Stat 5b mRNA has been reported for both muscle and mammary tissue. Stat 5a is critically involved in a variety of physiological functions, including reproduction, lactation, immune function and somatic growth.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :Stat5a/b (A688) polyclonal antibody detects endogenous levels of Stat5a/b protein.

BiowMW :~ 95 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :Immune Cell Signaling,Jak Stat ：IL-6 Receptor Signaling,T cell receptor signaling,

Alternative Name :Signal transducer and activator of transcription 5A; STAT5A; STAT5; Signal transducer and activator of transcription 5B; STAT5B

Immunogen :Recombinant protein.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of Stat5a/b pAb at 1:500 dilution Lane1:PC3 whole cell lysate(40ug) Lane2:CT-26 whole cell lysate(40ug) Lane3:THP-1 whole cell lysate(40ug) Lane4:MCF-7 whole cell lysate(40ug)

Immunofluorescence analysis of MCF-7 cells using Stat5a/b (A688) antibody at dilution of 1:50.

P38γ modulates the lipid metabolism in non-alcoholic fatty liver disease by regulating the JAK–STAT signaling pathway

JournalFASEB JOURNAL

ApplicationWB

IF5.834

SpeciesMouse

PMID36527390