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S100 α (A18) polyclonal antibody

货号: BS1318

价格：￥ 1140

货期：现货（1-2个工作日）

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详细信息检测数据实验指南文献

No. :BS1318

Product Name :S100 α (A18) polyclonal antibody

Swiss-Prot :P23297

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :IHC IF

Application_all :IHC: 1:50~1:200 IF: 1:50~1:200

Background :The family of EF-hand type Ca2+-binding proteins includes calbindin (previously designated vitamin D-dependent Ca 2+-binding protein), S-100 α and β, calgranulins A (also designated MRP8), B (also designated MRP14) and C (S-100 like proteins), and the parvalbumin family members, including parvalbumin α and parvalbumin β (also designated oncomodulin). The S-100 protein is involved in the regulation of cellular processes such as cell cycle progression and differentiation. Research also indicates that the S-100 protein may function in the activation of Ca2+ induced Ca2+ release, inhibition of microtubule assembly and inhibition of protein kinase C mediated phosphorylation. Two S-100 subunits, sharing 60% sequence identity, have been described as S-100α chain and S-100β chain. Three S-100 dimeric forms have been characterized, differing in their subunit composition of either two α chains, two β chains or one α and one β chain.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :S100 α (A18) polyclonal antibody detects endogenous levels of S100 A1 protein.

BiowMW :~ 10 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Protein S100-A1; S-100 protein alpha chain; S-100 protein subunit alpha; S100 calcium-binding protein A1; S100A1; S100A

Immunogen :Synthetic peptide, corresponding to the N-terminal of Human S100 α.

Conjugate :Unconjugated

Modification :Unmodification

Immunohistochemistry (IHC) analyzes of S100 α (A18) pAb in paraffin-embedded human breast carcinoma tissue at 1:50.

Immunohistochemical detection of S100A1 in the postmortem diagnosis of acute myocardial infarction

JournalDiagnostic Pathology

ApplicationIHC

IF2.335

SpeciesRat

PMID23683996
Involvement of MAPK ERK Activation in Upregulation of Water Channel Protein Aquaporin 1 in a Mouse Model of Bell’s Palsy

JournalJournal Of Molecular Neuroscience

ApplicationIF

IF2.678

SpeciesMouse

PMID25527444
iASPP overexpression is associated with clinical outcome in spinal chordoma and influences cellular proliferation, invasion, and sensitivity to cisplatin in vitro

JournalOncotarget

ApplicationIHC

IF0

SpeciesHuman

PMID28978123