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PYK2 (R875) polyclonal antibody（KU）

货号: BS1306

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS1306

Product Name :PYK2 (R875) polyclonal antibody（KU）

Swiss-Prot :Q14289

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :Pyk2 is a protein tyrosine kinase related to Focal Adhesion Kinase (p125 FAK). Pyk2 is highly expressed in the central nervous system. It is phosphorylated on tyrosine residues in response to various stimuli that elevate intracellular calcium concentration, as well as by protein kinase C activation.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :PYK2 (R875) polyclonal antibody detects endogenous levels of PYK2 protein.

BiowMW :~ 116 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :G Protein-coupled Receptors Signaling to MAPK Erk,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,

Alternative Name :Cell adhesion kinase beta; CAK beta; Calcium-dependent tyrosine kinase; CADTK; Related adhesion focal tyrosine kinase; RAFTK; PYK2; FAK2; PYK2; RAFTK

Immunogen :Synthetic peptide, corresponding to amino acids 360-418 of Human TFDP1.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of PYK2 (R875) pAb at 1:500 dilution Lane1:C6 whole cell lysate(40ug) Lane2:The Brain tissue lysate of Mouse(40ug) Lane3:MCF-7 whole cell lysate(40ug) Lane4:A375 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of PYK2 (R875) pAb in paraffin-embedded human breast carcinoma tissue at 1:50.