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NFkB-p65 (T429) polyclonal antibody（KU）

货号: BS1254

价格：￥ 1140

货期：现货（1-2个工作日）

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No. :BS1254

Product Name :NFkB-p65 (T429) polyclonal antibody（KU）

Swiss-Prot :Q04206

Host :Rabbit

Reactivity :Human,Mouse

Applications :WB IHC

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200

Background :p65 is a subunit of the nuclear factor kappa B. The transcription factor NFkB is widely recognized as a critical mediator of immune and inflammatory responses. In most cell types, NFkB is found in the cytoplasm where it is associated with an inhibitory prd in many tissues. A high proportion of spontaneous NIH/3T3 transformants overexpress c-Met and by transfection analysis the c-Met proto-oncogene has been shown to exhibittransforming activity.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :NFκB-p65 (T429) polyclonal antibody detects endogenous levels of NFκB-p65 protein.

BiowMW :~ 60, 75 kDa

Note :For research use only, not for use in diagnostic procedure.

Pathway :NF-kB Signaling,NF-kB Signaling,Immune Cell Signaling,Signaling Pathways Activating p38 MAP KinaseSTING Signaling,T cell receptor signaling,Inhibition of Apoptosis,Contribution of Soluble Factors to EMT,Toll-like Receptor signaling,

Alternative Name :p65; p65 NF kappaB; p65 NFkB; RELA; NFKB P65; Transcription Factor p65; Nuclear factor NF-kappa-B p65 subunit; NFkB-p65; NFKB3

Immunogen :Synthetic peptide, corresponding to amino acids 400-450 of Human NFkB-p65.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of NFkB-p65 (T429) polyclonal antibody at 1:500 dilution Lane1:CT26 whole cell lysate(40ug) Lane2:BV2 whole cell lysate(40ug) Lane3:The Kidney tissue lysate of Mouse(40ug) Lane4:NIH-3T3 whole cell lysate(40ug) Lane5:H9C2 whole cell lysate(40ug) Lane6:L02 whole cell lysate(40ug) Lane7:HepG2 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of NFκB-p65 (T429) pAb in paraffin-embedded human breast carcinoma tissue.

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