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MMP-23 (V371) polyclonal antibody（KU）

货号: BS1237

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS1237

Product Name :MMP-23 (V371) polyclonal antibody（KU）

Swiss-Prot :O75900

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB

Application_all :WB: 1:500~1:1000

Background :Matrix metalloproteinases (MMPs) are highly homologous Zn2+ endopeptidases involved in extracellular matrix breakdown. MMP mediated extracellular remodeling occurs in normal physiological processes, such as embryonic development, reproduction and tissue remodeling, and disease processes, including arthritis and metastasis. MMP-23 exhibits sequence similarity with most MMPs, but displays a difference in domain structure. The MMP-23 protein contains prepro-, catalytic, cysteine-rich, Interleukin-1 receptor-related and proline-rich domains. Lacking a recognizable signal sequence, MMP-23 has a short prodomain. In addition, MMP-23 contains a single cysteine residue that can be part of the cysteine-switch mechanism operation for maintaining enzyme latency. MMP-23 is a membrane-anchored glycoprotein with type II topology. Subcellular localization is predominantly perinuclear.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :MMP-23 (V371) polyclonal antibody detects endogenous levels of MMP-23 protein.

BiowMW :~ 44 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Matrix metalloproteinase-23; MMP 23; Femalysin; MIFR-1; Matrix metalloproteinase-21; MMP-21; Matrix metalloproteinase-22; MMP-22; Matrix metalloproteinase-23, soluble form; MMP23A; MMP21; MMP23B; MMP21; MMP22; MMP23

Immunogen :Synthetic peptide, corresponding to amino acids 341-390 of Human MMP-23.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of MMP-23 (V371) polyclonal antibody at 1:500 dilution Lane1:BV2 whole cell lysate(40ug) Lane2:H9C2 whole cell lysate(40ug) Lane3:PC3 whole cell lysate(40ug) Lane4:SK-OVCAR3 whole cell lysate(40ug)