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MAGEA1 (F293) polyclonal antibody

货号: BS1217

价格：￥ 1140

货期：现货（1-2个工作日）

25ul 50ul 100ul 200ul

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详细信息检测数据实验指南文献

No. :BS1217

Product Name :MAGEA1 (F293) polyclonal antibody

Swiss-Prot :P43355/Q8WWH6

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :IHC

Application_all :IHC: 1:50~1:200

Background :The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors, and based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens and are expressed in tumors of different histologic types, but not in normal tissues, with the exception of testis and placenta. Although a large number of MAGE genes have now been identified and extensively studied in tumors of various origin, their function in normal cells remains unknown.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :MAGE-1 (F293) polyclonal antibody detects endogenous levels of MAGE-1 protein. This antibody also detects endogenous levels of Tumor antigen MAGE-N.

BiowMW :~ 34, 46 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Melanoma-associated antigen 1; Antigen MZ2-E; Cancer/testis antigen 1.1; CT1.1; MAGE-1 antigen; MAGEA1; MAGE1; MAGE1A; Tumor antigen MAGE-N

Immunogen :Synthetic peptide, corresponding to amino acids 280-320 of Human MAGE-1.

Conjugate :Unconjugated

Modification :Unmodification

Immunohistochemistry (IHC) analyzes of MAGE-1/Tumor antigen MAGE-N (F293) pAb in paraffin-embedded human breast carcinoma tissue.

Post-transcriptional regulation of cancer/testis antigen MAGEC2 expression by TRIM28 in tumor cells

JournalBmc Cancer

ApplicationWB

IF2.933

SpeciesHuman

PMID30309319