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JunD (V249) polyclonal antibody

货号: BS1198

价格：￥ 1140

货期：现货（1-2个工作日）

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说明书 MSDS SHIP

详细信息检测数据实验指南文献

No. :BS1198

Product Name :JunD (V249) polyclonal antibody

Swiss-Prot :P17535

Host :Rabbit

Reactivity :Human,Mouse,Rat

Applications :WB IHC IP

Application_all :WB: 1:500~1:1000 IHC: 1:50~1:200 IP: 1:50~1:200

Background :The activator protein-1 (AP-1) transcription factor consists of either Jun/Jun homodimers or Fos/Jun heterodimeric complexes. Homo- and heterodimers bind to the TGACTCA consensus sequence present in numerous promoters and initially identified as the phorbol ester tumor promoter response element (TRE). Jun B and Jun D have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. All three form heterodimers among themselves and with c-Fos and other members of the Fos gene family. Studies suggest that the two forms of Jun D may be due to internal initiation of translation.

Product :Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification&Purity :The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage&Stability :Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity :JunD (V249) polyclonal antibody detects endogenous levels of JunD protein.

BiowMW :~35 kDa

Note :For research use only, not for use in diagnostic procedure.

Alternative Name :Transcription factor jun-D; JUN D

Immunogen :Synthetic peptide, corresponding to amino acids 220-270 of Human JunD.

Conjugate :Unconjugated

Modification :Unmodification

Western blot (WB) analysis of JunD (V249) polyclonal antibody in extracts from A549 cells.

Immunohistochemistry (IHC) analyzes of JunD (V249) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.

免疫沉淀（IP）

免疫组织化学（IHC）